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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCC9 All Species: 20.3
Human Site: T489 Identified Species: 44.67
UniProt: O60706 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60706 NP_005682.2 1549 174223 T489 K S T L D Y S T E R L K K T N
Chimpanzee Pan troglodytes XP_001149571 1549 174407 T489 K S T L D Y S T E R L K K T N
Rhesus Macaque Macaca mulatta XP_001098888 1549 174520 T489 K S T L D Y S T E R L K K T N
Dog Lupus familis XP_543765 1549 174367 T489 K S T L D Y S T E R L K K T N
Cat Felis silvestris
Mouse Mus musculus P70170 1546 174220 S486 Q K S T L D Y S T E R L K K T
Rat Rattus norvegicus Q63563 1545 174100 S485 Q K S T L D Y S T E R L K K T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5F364 1525 170953 M442 D L A T Y I N M I W S A P L Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001025325 1558 175224 T495 K S T L D Y S T D R L K K T T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786897 1561 174517 K495 I R S D K R L K S S N E L L Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q7GB25 1514 168556 I459 L V A T I I S I L V T I P L A
Baker's Yeast Sacchar. cerevisiae P39109 1515 171103 I468 L N S F L M R I Q K K L Q K S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.2 97.9 98.8 N.A. 96.7 96.9 N.A. N.A. 33.9 N.A. 80.1 N.A. N.A. N.A. N.A. 35.6
Protein Similarity: 100 99 98.8 99.3 N.A. 97.8 98.1 N.A. N.A. 54.4 N.A. 88.6 N.A. N.A. N.A. N.A. 56.4
P-Site Identity: 100 100 100 100 N.A. 6.6 6.6 N.A. N.A. 0 N.A. 86.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 26.6 26.6 N.A. N.A. 6.6 N.A. 93.3 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 31 30.9 N.A.
Protein Similarity: N.A. N.A. N.A. 51.9 52.2 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 19 0 0 0 0 0 0 0 0 10 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 10 46 19 0 0 10 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 37 19 0 10 0 0 0 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 10 19 0 19 10 0 0 10 0 0 0 % I
% Lys: 46 19 0 0 10 0 0 10 0 10 10 46 64 28 0 % K
% Leu: 19 10 0 46 28 0 10 0 10 0 46 28 10 28 0 % L
% Met: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 0 0 10 0 0 0 10 0 0 0 37 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 19 0 0 % P
% Gln: 19 0 0 0 0 0 0 0 10 0 0 0 10 0 19 % Q
% Arg: 0 10 0 0 0 10 10 0 0 46 19 0 0 0 0 % R
% Ser: 0 46 37 0 0 0 55 19 10 10 10 0 0 0 10 % S
% Thr: 0 0 46 37 0 0 0 46 19 0 10 0 0 46 28 % T
% Val: 0 10 0 0 0 0 0 0 0 10 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 46 19 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _